Co-micelle Technology by Hyaluronic Acid (HA) Nanogel (trade name SonanosTM) Solubilize as much of a Poorly Water-Soluble Drug as Possible with as Little as Possible

AAPS ePoster Library, Kohei Yabuuchi, 403201

Dexamethasone-Loaded Colon-Targeting UniORV® with Improved Anti-inflammatory Effects and Reduced Risks of Systemic Side Effects

AAPS ePoster Library, Hideyuki Sato, 403200

Long-Acting Drug Delivery System for Subcutaneous, Intravitreal, and Intra-articular Administration using Hyaluronic Acid-Based In Situ Gelling Nanosuspension Formulation of Water-Insoluble Drugs

AAPS ePoster Library, Takashi Nakai, 403199

Regulatory Challenges with Formulation Assessment of Parenteral Drug Products During ANDA Review: Case Studies and Considerations

AAPS ePoster Library, Xinran Li, 403198

Transdermal Permeability Assay of LK 467, a Selective and Potent Agonist of the Melanocortin 1 Receptor, Demonstrating the Efficacy of Topical Application

AAPS ePoster Library, Vineetha Guttha, 403197

Preparation and Evaluation of Dexamethasone Phosphate-Encapsulated Liposomal Gel Formulation for Intratympanic Delivery

AAPS ePoster Library, Yu-mi Bae, 403196

Bioinspired Nanoerythrocytes for Metabolic Microenvironment Remodeling and Long-Term Prognosis Promoting of Acute Ischemic Stroke

AAPS ePoster Library, Peixin Liu, 403195

Optimizing Carvedilol Dosing Following Gastric Bypass Surgery Using Population-Based PK/PD Modeling

AAPS ePoster Library, Priscila Yamamoto, 403194

An Improved Spray Dried Dispersion Model: Integrating Machine Learning to Predict Optimized Process Parameters

AAPS ePoster Library, Hannah Worrest, 403193

Development, Optimization and Validation of UPLC Method for Determination of Flavonoids from Seed Extracts of Elite Pongamia pinnata Seeds

AAPS ePoster Library, Harika Magam, 403191

Analysis of Semi- and Non-Volatile Leachables via an Enhanced HPLC-UV Method

AAPS ePoster Library, Sarah Jenny, 403190

Crystallization Kinetics of Amorphous Lactose: The Difference between α and β Anomers

AAPS ePoster Library, Zhenxuan Chen, 403189

In-Depth Characterization of PS-80 Degradation in Biologics Drug Products by Reversed Phase Liquid Chromatography Coupled with Charge-Reduction High Resolution Mass Spectrometry

AAPS ePoster Library, Rong-Sheng Yang, 403188

Development of a High Purity, High Productivity Cell Culture Media Additive

AAPS ePoster Library, Joshua Katz, 403187

Optimizing Discovery Bioanalytical Strategy for Macrocyclic Peptides and Degraders with Orbitrap High Resolution Mass Spectrometry

AAPS ePoster Library, Xing Zhang, 403186

Quantitative Characterization of Oligonucleotide Transport Vehicle (OTV) In Vivo Distribution and Pharmacokinetics using Ultra-sensitive, Plate-Based Bioanalytical Methods

AAPS ePoster Library, Alexander Stergioulis, 403185

Quantitative Analysis of GalNAc-siRNA Conjugates in Tissue Homogenate Using Two-Dimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry

AAPS ePoster Library, Jinlian Lu, 403184

Highly Sensitive Analysis Using EVOSEP-LC/MS Assay for Targeted PD-L1 and PD1 Expression Level for Predicting Response to Immune Checkpoint Inhibitors

AAPS ePoster Library, Shane Karnik, 403183

scRNA-seq - A Potential ELISpot Alternative?

AAPS ePoster Library, Peter Burkard, 403182

Improving the Solubility and Absorption of the Low-Solubility Compound Aripiprazole by Electrospinning Nanofiber Formulation

AAPS ePoster Library, Hideo Takeda, 403181

Impact of Tooling Size on the Heckel Profile and Derived Compressibility Parameters

AAPS ePoster Library, Piero Piccinni, 403180

Temperature-Dependent Terahertz Time-Domain Spectroscopy as a Tool to Predict Crystallisation Tendencies of Amorphous Drugs

AAPS ePoster Library, Haseeb Mahmood, 403179

Development and Optimization of an In Vitro Release Assay for Evaluation of Liposomal Irinotecan Formulation

AAPS ePoster Library, Vivian Juang, 403178

Fabrication of Caffeine Transdermal Film Using the Hot-Melt Extrusion and Fused Deposition Modeling 3D Printing

AAPS ePoster Library, Sooyeon Chung, 403177

Remote Loading of Setmelanotide in Poly(lactic-co-glycolic acid) Microspheres for Long-Term Obesity Control

AAPS ePoster Library, Shuying Wang, 403176

In Vivo Confirmation of the Permeation Enhancement Capacity of Labrafac™ MC60

AAPS ePoster Library, Philippe Caisse, 403175

Improvement of Mechanical Properties of MRTX0902 by Crystalline Form Selection and Particle Engineering

AAPS ePoster Library, Aastha Chadha, 402967

Role of PLGA Variability in Controlled Drug Release from Dexamethasone Intravitreal Implants

AAPS ePoster Library, Feng Zhang, 393575

Microbicide-Containing SMART Gel for Female-Controlled Multipurpose Prevention

AAPS ePoster Library, Burcu Uner, 393574

Combination Therapy of BRD4/PI3K Dual Inhibitor and Novel Tubulin Inhibitor Efficiently Treats Chemo-Resistant Pancreatic Cancer

AAPS ePoster Library, Yashwardhan Ghanwatkar, 393529

A Versatile Room Temperature Stable Lipid Nanoparticle COVID-19 Protein-Based Vaccine

AAPS ePoster Library, RajivNayar Engimata, 393531

Design of Citric Acid Coated Superparamagnetic Iron Oxide Nanoparticles for the Treatment of Lung Cancer

AAPS ePoster Library, Mitali Patel, 393532

Encapsulation of Cabazitaxel in Polymeric Nanoparticles and Its Biological Effect on Prostate Cancer Cells

AAPS ePoster Library, Priscyla Marcato, 393533

Formulation and Evaluation of Pulsatile Release Melatonin Capsule (Single and Multiple Unit Pellets) for Circadian Rhythm Sleep Disorders

AAPS ePoster Library, Kristina Kannheiser, 393534

Multiphysics Modeling and Experimental Design of Novel Ocular Drug Delivery Systems for Glaucoma Treatment

AAPS ePoster Library, Prateek Jha, 393535

Preparation of Nanoparticles Based on Krafft Point of Nonionic Polyoxyethylated Amphiphiles

AAPS ePoster Library, Jessica Li, 393536

β-catenin Inhibition Using XAV939 Nanoparticle Promotes Immunogenic Cell Death and Suppresses Tumor Progression

AAPS ePoster Library, Xuejia Kang, 393537

Development of a Novel Repeat-Action Oral Drug Delivery System for Naproxen and Esomeprazole

AAPS ePoster Library, Yejin An, 393539

Enhanced Dissolution of Amphotericin B through Development of Amorphous Solid Dispersions Containing Polymer and Surfactants

AAPS ePoster Library, Mikayla Smith, 393540

Impact of Structural Relaxation in Amorphous Solid Dispersions

AAPS ePoster Library, Tianyun Zhang, 393541

Micellar Codelivery of DQ, a Disulfiram Based Prodrug with In Situ Copper Ions Chelation for Cancer Therapy

AAPS ePoster Library, Qi Wang, 393542

Role of Citric Acid in Enhancing Drug Performance: A Double-Edged Sword?

AAPS ePoster Library, Vishal Rathod, 393543

Understanding the Role of Water on the Molecular Mobility of Polymer Systems with Terahertz Spectroscopy

AAPS ePoster Library, Supawan Santitewagun, 393544

Nanosac: A Soft Nanocarrier for Systemic siRNA Delivery to Solid Tumors

AAPS ePoster Library, Hytham Gadalla, 393528

Heat Shock Protein-Loaded Mitochondria Containing Microvesicles Protect the Blood-Brain Barrier in Ischemic Stroke

AAPS ePoster Library, Kandarp Dave, 393527

Drug Nanocrystals Enable Rapid Formulation Transfer from Liquid-Phase Pre-clinical Testing to First-in-Human Solid Dosage Forms

AAPS ePoster Library, Stanislav Chvíla, 393526

Monitoring of Lidocaine Transport through Dermis and Subcutis into Muscle Tissue after Application via Topical Delivery Systems

AAPS ePoster Library, Thomas Birngruber, 403143

Improving Aerodynamic Performance with Spray-Dried Corrugated Chitosan Microparticles

AAPS ePoster Library, Yu-Rim Choi, 403145

Understanding the Role of Particle Size of Poloxamer P407 on Properties of Tablet Prepared by Direct Compression Process

AAPS ePoster Library, Ming Ji, 403146

Impact of Food on the Release and Bioaccessibility of an Oral BCS Class IV Compound formulated from Different Conventional and Enabling Formulations using the Dynamic Gastrointestinal Model Tiny-TIMsg

AAPS ePoster Library, Vanessa Mancini, 403147

Digestion Is a Critical Element for Absorption of Cinnarizine from Supersaturated Lipid-Based Type I Formulations

AAPS ePoster Library, Felix Paulus, 403148

Predicting the Relative in Vivo performance of Nanoformed and Crystalline Bulk Piroxicam Solid Suspensions from in Vitro Flux Measurements

AAPS ePoster Library, Balint Sinko, 403149

The Effect of Cancer-Associated Cachexia on the Pharmacokinetics of Extra-vascularly Administered Monoclonal Antibodies

AAPS ePoster Library, Adeoluwa Adeluola, 403150

Metformin Induced-Oxidative Stress Modulates LNCaP Cellular Redox Status and Suppressed Cell Growth

AAPS ePoster Library, Sashana Dixon, 403151

Anti-cancer Sonosensitive DOX-Loaded Liposomes to Avoid Systemic Immunosuppression

AAPS ePoster Library, Jeongjin Lee, 403152

Advancing Lung Cancer Therapy: Development and Optimization of Lorlatinib Loaded Inhaled Nanostructure Lipid Carriers (NLC) Using Design of Experiment Approach

AAPS ePoster Library, Akanksha Ugale, 403154

Navigating Thermal Binder Selection for Rational Design of a Twin-Screw Melt Granulation Process

AAPS ePoster Library, James Sandlin, 403155

Combining Machine Learning and Backgrounded Membrane Imaging: A Case Study in Comparing and Classifying Different Types of Biopharmaceutically Relevant Particles

AAPS ePoster Library, Sandy Hutchison, 403156

Critical Manufacturing Parameters and Their Impacts on the Product Attributes of Bupivacaine Multivesicular Liposomal Formulation (Exparel®)

AAPS ePoster Library, Ziyun Xia, 403157

Doxorubicin HCl Release from Liposomal Doxorubicin Formulations – Autonomous Capillary Electrophoretic (CE) In Vitro Release Test (IVRT) Method

AAPS ePoster Library, Savithra Jayaraj, 403158

Quantitation of Ethylene Oxide and Nitrosamines in Excipients and Pharmaceutical Products Using SIFT-MS

AAPS ePoster Library, Christopher Williams, 403160

Quantum Electrochemical Spectroscopy (QES): A Novel Approach for Enhanced Detection and Evaluation of Drug-Induced Liver Injury (DILI)

AAPS ePoster Library, Chaitanya Gupta, 403161

Repeatability and Reproducibility of Simulated Fasted and Fed State Gastrointestinal Conditions and Paracetamol Bioaccessibility in the Dynamic In Vitro Models TIM-1 and Tiny-TIMsg

AAPS ePoster Library, Tânia Martins Garcia, 403162

Transforming Growth Factor-Beta (TGF-β) as a Potential Therapeutic Target of Methylseleninic Acid and Seleno-l-Methionine in Clear Cell Renal Cell Carcinoma

AAPS ePoster Library, Aseel Rataan, 403163

Next Level Drug Research in an Ex Vivo Tissue Gut-on-a-Chip Model: Advanced Applications of the Intestinal Explant Barrier Chip (IEBC)

AAPS ePoster Library, Esmée Wierenga, 403164

Preclinical Pharmacokinetic Study and Lung Penetration of Coumarin Extracted of Zanthoxylum tingoassuiba

AAPS ePoster Library, Francine Azeredo, 403165

Assessing the In Vitro Performance of Solid Dosage Forms Over-Encapsulated with the ID-Cap System for Improved Compliance

AAPS ePoster Library, Kajal Gupta, 403166

A Simulation-Based Decision Guide to Evaluate Missing Data in Bioequivalence Studies

AAPS ePoster Library, Minh Ngoc Le, 403167

Poloxamer 188 in Amorphous Solid Dispersions of Efavirenz and HPMC-AS Improves In Vitro Dissolution of the Drug but Does Not Affect In Vitro Permeation nor In Vivo Absorption

AAPS ePoster Library, Anette Müllertz, 403168

Hot and Cold Formulation of Biologics for the Optimization of Drying Technologies

AAPS ePoster Library, Paulo Lino, 403169

Development of Antibody Conjugated Nanoparticles for Delivery of Nucleic Acid for Stimulation of Perivascular Macrophages

AAPS ePoster Library, Muskan Badola, 403170

A New and Sustainable Twin Screw Wet Granulation Method Making Subsequent Drying Obsolete

AAPS ePoster Library, Felicitas Guth, 403171

Spatial Heterogeneity in Drug Crystallization in Extrudates Prepared by Hot Melt Extrusion

AAPS ePoster Library, KRISHNA KUMAR NAGARAJAN SREE KALA, 403172

Effect of LNP Components on mRNA-Mediated Protein Expression of Lipid Nanoparticles in Different Organs

AAPS ePoster Library, Ruchi Sharma, 403174

Simultaneous XRD-DSC Analysis Identifies Correct Solid Form Dissolution in Polymer

AAPS ePoster Library, Mustafa Bookwala, 393525

A Promising Peptide-Based Universal Vaccine against MERS-CoV and SARS-CoV2 Coronaviruses

AAPS ePoster Library, Abdulaziz Aldayel, 393524

Assessment of In Vitro and In Vivo Pre-clinical Pharmacokinetics of EPZ015666; a Novel Small Molecule for Medulloblastoma Treatment

AAPS ePoster Library, Pratiksha Kshirsagar, 393514

Comparing a t-Distribution Based Bayesian Approach with the Two One-Sided t-Test (TOST) for Bioequivalence Studies in Real-World Datasets

AAPS ePoster Library, Meng Hu, 393513

Physiologically Based Biopharmaceutics Modeling of BCS Class I Extended-Release Drug Products: A Preliminary Exploration

AAPS ePoster Library, Hansong Chen, 393512

Assessing In Vitro Release Testing (IVRT) in Bioequivalence Studies for Complex Products - Considerations for Ophthalmic versus Topical Dermatological Dosage Forms

AAPS ePoster Library, Josephine Aimiuwu, 393511

Quantitative Determination of Microcrystalline Cellulose in Drug Products by Chemometrics Analysis of Raman Spectroscopy

AAPS ePoster Library, Zhouming Zhao, 393510

Analysis of Manufacturing Deficiencies for Immediate Release Tablets in Abbreviated New Drug Applications

AAPS ePoster Library, Zhouxi Wang, 393509

Process Analytical Technology for Inline Aerodynamic Particle Size Measurements during Spray Drying

AAPS ePoster Library, Cody Prather, 393508

Systematic Root Cause Analysis for Investigation of Contamination Peak in an Ovicidal Topical Product

AAPS ePoster Library, Niveditha Mullapudi, 393507

Co-processing PVP with Maltodextrin during Spay-Drying Reduces the Impact of Humid Weather on Product Attributes

AAPS ePoster Library, Rahima Khatun, 393506

Leachable Analysis of Ethylene Vinyl Acetate Infusion Bags by GC-FID-MS and LC-UV-MS

AAPS ePoster Library, Steve Grossman, 393505

An In Vitro Model for Acetaminophen Dissolution from Overdosed Oral Formulations

AAPS ePoster Library, Maja Chronowska, 393504

Transdermal Delivery of Cannabidiol from Marketed Cannabidiol Patches

AAPS ePoster Library, Nisarg Modi, 393503

Preparation of Ketoprofen Polymer Based Solid SEDDS Using Twin Screw Melt Granulation to Improve the Solubility and Permeability

AAPS ePoster Library, Lakshmi Priyanka Gudipati, 393502

Microfluidics Generated Aspirin Loaded Albumin Nanoparticles for Targeted Brain Delivery in the Treatment of Ischemic Stroke

AAPS ePoster Library, Dedeepya Pasupuleti, 393501

Formulation and Evaluation of Prochlorperazine Maleate Sustained Release Mucoadhesive Buccal Films Using Hot Melt Extrusion

AAPS ePoster Library, Ajayreddy Kolipaka, 393500

Effects of Monomer on PLGA Based Long-Acting Injectables’ Release and Stability

AAPS ePoster Library, Cory Mahnen, 393499

Co-solvents for Microemulsion Formulations containing Ethoxylated Castor Oils for Transdermal Drug Delivery

AAPS ePoster Library, Ashish Jayaraman, 393498

A Thermosensitive Hydrogel Formulation of Phage and Colistin Combination for Management of Multidrug-Resistant Acinetobacter baumannii Wound Infection

AAPS ePoster Library, Subhankar Mukhopadhyay, 393497

A Novel Octreotide Conjugated PEGylated Liposomal Paclitaxel for Targeted Pancreatic Cancer Treatment

AAPS ePoster Library, Xin Gu, 393496

Multi-functionalized Cationic Chitosan Polymeric Micelles for pVGF Delivery to the Brain through the Intranasal Route

AAPS ePoster Library, Avinash Gothwal, 393495

Cisplatin-Loaded Dendritic Mesoporous Silica Nanoparticles for Improved Drug Delivery to Ovarian Cancer Metastasis

AAPS ePoster Library, Mittal Darji, 393494

Shear-Induced Crystallization of Amorphous Indomethacin

AAPS ePoster Library, Ruilin Chao, 393493

Fusogenic Liposomes as an Approach to Enhance the Efficacy of Antimicrobials

AAPS ePoster Library, Ahmed Amer, 393492

Drug Loading Efficiency of a Topical Anorectal Wipes: A Wipe Impregnation Study

AAPS ePoster Library, Sai Akkineni, 393490