Common Deficiencies Using Alternative Bioequivalence Approach for Metered Dose Inhaler in Abbreviated New Drug Applications

AAPS ePoster Library, Li Xia, 403142

Aceclofenac-Loaded Nanoparticulate Carriers with Enhanced Solubilization Using Deep Eutectic Solvents for Improved Transdermal Delivery

AAPS ePoster Library, Jeong-Su Ryu, 403141

Formulation, Optimization, and In Vitro Studies of Atorvastatin Calcium Cocrystals

AAPS ePoster Library, Aly Nada, 403140

Encapsulation in Glucan Particles Promotes Solubility and Anti-biofilm Activity of Natural Poly-actives In-vitro

AAPS ePoster Library, Eva Kralova, 403139

Gatifloxacin Nanoemulsions Prepared by Hot Melt Extrusion/Hot-Homogenization for Bacterial Conjunctivitis.

AAPS ePoster Library, Mihir Ghonge, 403138

Investigating the Effect of Plasticizer Type and Concentration on Kollicoat® SR Films Prepared by Film Casting Technique

AAPS ePoster Library, Aslihan Arslan, 403137

A Rational and Data-Driven Approach to Formulation of Therapeutic Peptides

AAPS ePoster Library, Tania Lind, 403136

Disposition and Metabolism of the Cardiac Myosin Inhibitor Aficamten in Humans

AAPS ePoster Library, Donghong Xu, 403135

Strategies for Data Treatment of RTD Curves for Pharmaceutical Applications

AAPS ePoster Library, Sonia M. Razavi, 403134

Improvement upon a Multi-residue Method for Nitrosamine Analysis in Losartan Drug Product Using an Enhanced LC/MS/MS System

AAPS ePoster Library, David Weil, 403133

Assessing Stress-Induced Amorphization and Excipient Functionality in Tablet Matrices Using Correlative Microscopy Analysis

AAPS ePoster Library, Nikhil Loka, 403132

Electrophotographic 3D Printing of Pharmaceutical Films

AAPS ePoster Library, Patricija Januskaite, 403131

Improvements to PS80 Detection in Drug Product Formulations: A Mixed Mode High-Performance Liquid Chromatography Method for the Quantification and Improvement in the Detection of Polysorbates

AAPS ePoster Library, Joey Campbell, 403130

Using Enzymes to Accelerate PS80 Degradation and Elucidate Mechanistic Impacts of PS80 Degradants on Protein Stability via Thermal- and Agitation-Induced Aggregation

AAPS ePoster Library, Caitlin Wood, 403129

A Model-Based and Quality-by-Design Compatible Lyophilization Cycle Development Strategy for Biopharmaceuticals

AAPS ePoster Library, Andrea Hawe, 403128

Development of an Ultrasensitive qPCR Method to Identify and Quantify Point Mutation in Circulating Tumor DNA

AAPS ePoster Library, JINPING LAI, 403127

A Comprehensive Array of Bioanalytical Assays to Assess the Pharmacokinetic Properties of Antibody-Drug Conjugates In Vivo and In Vitro

AAPS ePoster Library, Jiaqi Yuan, 403126

Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control

AAPS ePoster Library, Hongye Li, 403125

Toward Development of a New QCM-D Based Method for Rapid Detection of a Novel Biomarker of Morbidity and Mortality Risk in Sepsis Patients

AAPS ePoster Library, Eman Kamel, 403124

Qualification of a Neurology 2-Plex B (Nf-L, GFAP) Quanterix Simoa® Assay Using a Novel Approach

AAPS ePoster Library, Christian Braithwaite, 403123

Barrier Properties of Pharmaceutical Polymers – Novel Applications for Protecting Respiratory Membranes from Pathogens

AAPS ePoster Library, Qiong Tang, 403122

Tetrahydrocurcumin, a Metabolic By-Product of Curcumin, Shows Neuroprotection: A Potential Therapeutic Metabolite for Neurodegenerative Pathologies

AAPS ePoster Library, Suhrud Pathak, 403121

Effects of Testosterone on Kidney Monocarboxylate Transporter Expression

AAPS ePoster Library, Annie Lee, 403120

High-Throughput 3D Bioprinting of Corneal Stromal Equivalents

AAPS ePoster Library, Thanh Dinh, 403119

Computational Support to Identify Ternary Solid Dispersions of Hydroxypropyl Cellulose and Small Molecular Additives to Stabilize Challenging Drugs

AAPS ePoster Library, Edmont Stoyanov, 403117

Mini Tablets as a Compliant and Flexible Pediatrics Delivery System

AAPS ePoster Library, VIvek Patel, 403116

Antimicrobial and Angiogenic Silver Nanoparticles and Verapamil Double-Layered Electrospun/3D Printed Wound Healing Patch for Accelerated Wound Healing

AAPS ePoster Library, Afaf Madkour, 403115

Volumetric Printing and Non-destructive Dose Verification of Water-Soluble Vat Photopolymerized Tablets Based on Supramolecular Chemistry

AAPS ePoster Library, Anna Kirstine Jørgensen, 403114

Optimizing Microfluidic Process Parameters and Lipid-Cholesterol Composition for Lysozyme-Loaded Liposome Preparation

AAPS ePoster Library, Minji Choi, 403113

Solubility Enhancement of Atorvastatin Calcium Trihydrate by Melt Extrusion

AAPS ePoster Library, Vishal Thota, 403112

Development of 3D Printable Inks for Protein Delivery

AAPS ePoster Library, Riyad Alzhrani, 403111

Understanding the Impact of Accelerated Release Testing Conditions on Transport Properties and Release Mechanisms of Drug from Long-Acting Ethylene Vinyl Acetate Implants

AAPS ePoster Library, Angela Ren, 393523

Effect of Food on the Pharmacokinetics of Mitragynine in Rats

AAPS ePoster Library, Kanumuri Raju, 393515

Physiologically-Based Pharmacokinetic (PBPK) Modeling of Oral Absorption of 5-flucytosine to Support Development of a Sustained-Release Formulation for Treatment of Cryptococcal Meningoencephalitis

AAPS ePoster Library, Erik Sjögren, 393516

A Strategy for Optimizing Precompression Pressure Using In-Die Elastic Recovery

AAPS ePoster Library, Gerrit Vreeman, 393517

Development and Characterization of RVG9R-Tansferrin Liposomal Nanoparticles Encapsulating Plasmid GFP for Targeted Delivery to the Brain

AAPS ePoster Library, Jagdish Singh, 393518

Impact of Quantitative Differences in an Inactive Ingredient on the Performance of Topical Products Containing Lidocaine or Diclofenac Sodium

AAPS ePoster Library, Srinath Rangappa, 393520

Mechanism of Stabilization of Amorphous Solid Dispersion above the Overlap Concentration (c*): Delay of the First Nucleation Event

AAPS ePoster Library, Sichen Song, 393521

Rizatriptan Nasal Spray with Effective Olfactory Deposition for Improving Migraine Treatment

AAPS ePoster Library, Guanlin Wang, 393522

Triggering Mucosal Immunity: An Intranasal Combination Vaccine for COVID-19 and Influenza

AAPS ePoster Library, Revanth Singh, 393489

Effect of Atomic Layer Coatings on the Stability of Solid Myoglobin Formulations

AAPS ePoster Library, Manuel Alfaro, 403078

Mutant mRNA Encapsulated Aptamer Conjugated-Lipid Nanoparticles for Targeting Heart Cells

AAPS ePoster Library, Ilkin Tetik Altintop, 403079

Performance Evaluation of Different Diluents for the Direct Compression of Acetaminophen Tablets

AAPS ePoster Library, Achref Cherif, 403080

Crafting Lipid-Polymer Nanoparticles of HDAC Inhibitors for the Treatment of Retinitis Pigmentosa

AAPS ePoster Library, Md. Jobair Hossen Jony, 403081

A New Solid Dispersion Modelling Framework for In Vitro and In Vivo Oral Absorption Anticipation Adapted to pH-Sensitive Matrices

AAPS ePoster Library, Guillaume Louit, 403082

Development of Various Formulation Strategies/Approaches for an Extended Release of a Non-opioid Narcotic for the Treatment of Acute/Chronic Pain

AAPS ePoster Library, Nency Patel, 403083

Developing Degradable Microparticles for the Delivery of Inactivated H1N1 Virus and NKT Cell Agonist for Single Dose Vaccination

AAPS ePoster Library, Zachary Sparks, 403084

Determination of Microdystrophin (h-µD5) via Signature Peptide Analysis in Muscle Tissue by LC-MS/MS

AAPS ePoster Library, Alicia Bian, 403085

Comparison of Manual and Automated Nucleic Acid Extraction Methods

AAPS ePoster Library, Geng Li, 403087

Regulatory Perspective of Considerations in Endogenous Therapeutic Analyte Bioanalysis

AAPS ePoster Library, Chongwoo Yu, 403088

Permeability of Metformin across the Blood-Brain Barrier: Repurposing a Potential Neurotherapeutic for Ischemic Stroke

AAPS ePoster Library, Sejal Sharma, 393337

Lipid Nanoparticle Impurity Monitoring Using Single Quadrupole Mass Detection for Regulated Environments

AAPS ePoster Library, Ann Gray, 403090

Unveiling the Impact of Surface Chemistry on Adsorption of a Therapeutic Monoclonal Antibody Using a Quartz Crystal Microbalance

AAPS ePoster Library, Elham Taherian, 403091

Impact of Alternative Lubricants on Tablet Parameters Approaching the Over-Lubrication Problems in Continuous Direct Compression Processes

AAPS ePoster Library, Nuno Branco, 403092

Development of Iterative Optimization Technology Algorithms with a Small-Scale Feed Frame Simulator: Stagnant vs. Dynamic Pure Component Spectra

AAPS ePoster Library, Samuel Henson, 403093

Compendial Strategy to Define Composition and Quality of Polysorbates

AAPS ePoster Library, Tong (Jenny) Liu, 403094

Demonstration of MicroCoatTM Scalability: A Fixed Dose Combination of Taste Masked Artesunate-Amodiaquine Micropellets for Malaria Treatment in Paediatrics

AAPS ePoster Library, Kavil Patel, 403095

A Twin-Screw Melt Coating and Granulation Approach for High Dose Formulations with any Desired Release Profile

AAPS ePoster Library, Zankrut Vyas, 403096

Effect of pH on Metabolite Profiling and Identification of GalNAc Conjugated siRNA in In Vitro Metabolic System

AAPS ePoster Library, Weiqun Cao, 403097

Evaluation of In Vitro Protein Binding of STK-001, an Antisense Oligonucleotide, in Plasma and Cerebrospinal Fluid

AAPS ePoster Library, Qian Lin, 403098

Quantifying Clinical Trial Diversity of New Drugs Approved by the FDA

AAPS ePoster Library, Kay Olmstead, 403099

Case Study: Assessing Innovator vs. Biosimilar mAb Stability to Minimize Immunogenic Risk

AAPS ePoster Library, Ronald Soriano, 403100

Population Pharmacokinetic Model of Tacrolimus in Brazilian Bone Marrow Transplantation Patients: A Tool for Dosing Regimen Optimization

AAPS ePoster Library, Bibiana Araujo, 403101

Dual Functionality of Poloxamer 188 in Freeze Dried Protein Formulations: A Stabilizer in Frozen Solution and a Bulking Agent

AAPS ePoster Library, Jinghan LI, 403104

A Novel Approach for Targeted Pulmonary Delivery of Thymoquinone as Dry Powder Inhaler (DPI)

AAPS ePoster Library, Hamad Alyami, 403105

Development of a Novel Therapeutic Contact Lens with the Embedded-Drug Chamber as an Ophthalmic Drug Delivery System for Dry Eye Syndrome

AAPS ePoster Library, Ji Yeon Kim, 403107

Development of Nanofiber-Based, Anti-proliferative Sutures for Glaucoma Surgery

AAPS ePoster Library, Sri Vishnu Kiran Rompicharla, 403108

Unlocking the Potential of Co-processed Excipient and algorithm-based tool for Direct Compression Tablet Manufacturing

AAPS ePoster Library, Jason Wood, 403109

Physical Stability of Amorphous Pharmaceutical Formulations Insights into Crystallization Behavior

AAPS ePoster Library, Jianchao Xu, 403110

Reversible, Covalent DNA Condensation Approach via Chemical Linkers for Enhanced Gene Delivery to Nucleus

AAPS ePoster Library, Aaron Tasset, 393488

Mechanism and Generality of the Tabletability Flip Phenomenon

AAPS ePoster Library, Zijian Wang, 393487

Impact of Core Excipient Selection to Improve the Stability of a Moisture Sensitive Drug, Acetylsalicylic Acid

AAPS ePoster Library, Nitin Tayade, 393486

Engineering Gefitinib-Loaded Inhalable Solid Lipid Nanoparticles Using an Organic Solvent-Free Homogenization Method for the Treatment of Non-small Cell Lung Cancer

AAPS ePoster Library, Vasudha Prithipaul, 393485

Design and Evaluation of Colon-Targeted Dexamethasone Solid Dispersions for Inflammatory Bowel Disease

AAPS ePoster Library, Ahlam Zaid Alkilani, 393484

A Novel Approach to Formulation Screening of High Concentration Recombinant Human Heparan-N-Sulfatase (rhHNS) Using High-Throughput Devices

AAPS ePoster Library, Taeseung Yang, 393483

Understanding Release Mechanism and Development of Accelerated Release Tests for Long-Term Intrauterine Systems

AAPS ePoster Library, Rokon Zaman, 393482

Amorphous Solid Dispersion Physical Stability: Historical Examples and Shelf-Life Assessment

AAPS ePoster Library, Patrick Marroum, 393481

Better Together: Thermally Unstable Drug Granulated Using a Thermal Process?

AAPS ePoster Library, Adwait Pradhan, 393480

Optimization of USP Method for Quantitation of Beta Glucan Using a High-Performance Liquid Chromatography and Adapting to a Low Strength Semisolid Dosage Form

AAPS ePoster Library, Abhishek Mishra, 393479

Moisture Activated Dry Granulation: A Sustainable Process with Excipients and Process Consideration

AAPS ePoster Library, Kristina Kannheiser, 393478

The Effect of Sampling Cannula on In Vitro Dissolution Testing with USP Paddle Method

AAPS ePoster Library, Zongming Gao, 393477

CryoTEM Characterization of Vaccine Materials in Development

AAPS ePoster Library, Irene Chang, 393476

Activating 5-HT 1A Receptors as a Treatment for Fragile X Syndrome: A Preclinical Study in Fmr1 Knockout Mice

AAPS ePoster Library, Tanishka Saraf, 393475

Urinary MicroRNAs as Possible Biomarkers of Cisplatin-Induced Nephrotoxicity in Patients with Head and Neck Cancer

AAPS ePoster Library, Eder Pincinato, 393474

Endothelial Cell-Pericyte Interactions Regulate Brain Glucose Transport

AAPS ePoster Library, Lushan Wang, 393473

Understanding Mechanisms behind Low Conjugation Efficiencies of Thiol-Maleimide Reactions to Synthesize Antibody-Drug Conjugates

AAPS ePoster Library, Zekun Shao, 393472

The Search for HIV Latency Reversing Selective HDAC3 Inhibitors Through Virtual Screening

AAPS ePoster Library, Yushin Kim, 393471

Investigation of Molecular Interactions between Active Pharmaceutical Substances and Polymer Excipients Using 1H-NMR

AAPS ePoster Library, Selina Schmidt, 393470

Preparation and Optimization of Piperine Nanoparticles for Its Intranasal Delivery

AAPS ePoster Library, Jiahao Li, 393468

Formulation and Characterization of Non-invasive Nebulization Based Antiviral Drug, NSF207 Loaded Pegylated Nanoliposomal Suspension Product for Treatment of COVID-19

AAPS ePoster Library, Rama Kashikar, 393466

Computational Prediction of Initial Dissolution Performance after Co-milling with PVP

AAPS ePoster Library, Nicolas Pätzmann, 393464

A Single-Step Extrusion Process for Formulation Development of Self-Emulsifying Granules for Oral Delivery of a BCS Class IV Drug

AAPS ePoster Library, Vineet Kulkarni, 393463

Understanding the Relationship Between In Vitro Nasal Spray Characteristics and Intranasal Deposition in the Adult and Pediatric Populations

AAPS ePoster Library, Mohammad Hejazi, 393462

Mixing Differences during Preparation Methods have Implications on Successful Formation of Amorphous Solid Dispersions

AAPS ePoster Library, Ashwini Gumireddy, 393460

Characterizing the Drug Gastrointestinal Transfer Process after Disintegration of Solid Dose Units in the Fed State

AAPS ePoster Library, Shirin Nika Dietrich, 393459

Formulation Testing of TiO2-Free Film Coating Alternatives from Three Film Coat Vendors

AAPS ePoster Library, Jamie Abraham, 393458

Drug Crystal Growth Rate Decreases in the Presence of Coexistent Drug-Polymer Halogen and Hydrogen Bonds

AAPS ePoster Library, Mustafa Bookwala, 393457

A Comprehensive Bioanalytical Strategy of In Vivo Studies for RNAi Therapeutics in Early Discovery

AAPS ePoster Library, Nan Zhao, 403089

Formulation Development and Evaluation of Cannabidiol Oral Film Using Antisolvent and Solvent Casting Approaches

AAPS ePoster Library, Sujith RajBashetty, 393410

Characterization of Drug Release from a Blended Biodegradable Polymeric Film Using a Central Composite Design

AAPS ePoster Library, Kieran Chetty, 393411