Determining the Effect of Blade Fouling on the Approach to Steady State and Final Residence Mass within a Continuous Blender

AAPS ePoster Library, Lawrence Valeros, 393743

2D-LC as A Novel Analytical Platform for the Characterization of Complex Drug Substances: A Case Study with Glatiramer Acetate

AAPS ePoster Library, Tsdale Mehari, 403336

Regulatory Experience with Continuous Manufacturing and Real Time Release Testing for Dissolution in New Drug Applications

AAPS ePoster Library, Maziar Kakhi, 403335

Compaction Simulation of SDI-Based Formulations to Enable Material-, Time-, and Cost-Sparing Technical Transfer

AAPS ePoster Library, Allison DuRoss, 403334

Driving Timely Clinical Development: Simulation-Based Process Development and Tech-Transfer for Mini-Tablets in Capsules

AAPS ePoster Library, Peyman Aminpour, 403333

Using Experimentally Validated ML Modeling to Predict the Thawing Time of Biologics During Large Scale Freeze-Thawing Cycles

AAPS ePoster Library, Venkatraman Nagarajan, 403332

Research Strategy of Chiral PROTACs in Discovery Stage Based on Analysis Platforms of UPCC-MS/MS and UPLC-MS/MS

AAPS ePoster Library, Nan Zhao, 403331

Suitability of Isavuconazonium Sulfate as a Biopharmaceutics Classification System (BCS)-Based Biowaiver Candidate

AAPS ePoster Library, David Plano, 393755

Novel NanoSensoGel Engineered for Prevention of Chemotherapeutic-Induced Ototoxicity and Associated Hearing Loss

AAPS ePoster Library, Neeraj Thakur, 393754

Investigating Phase Separation of Trehalose during Lyophilization of Proteins Using Solid State NMR

AAPS ePoster Library, Rachana Sapkota, 393753

Evaluation of Stability and Physical Parameters of Sitagliptin IR Tablets Coated with Different Titanium Dioxide Free Coating Systems

AAPS ePoster Library, Nitin Tayade, 393752

Development of Hydrogel Polymer-Based Bilayer Gastro-Retentive Modified-Release Tablets

AAPS ePoster Library, Ching Sieu Tay, 393751

Assessing the Impact of Dry Particle Coating with Nano-Silica on Compaction Properties of Cohesive Active Pharmaceutical Ingredients

AAPS ePoster Library, Kellie Sluga, 393750

Metabolite Identification of R14 in Rat Urine after a Single Oral Administration to Rats Using UPLC-TOF MS/MS

AAPS ePoster Library, Yang Wang, 393749

Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon Cancer Cells

AAPS ePoster Library, Ahmad Shannar, 393748

Pharmacokinetics of Nervonic Acid, a Monounsaturated Fatty, in an Adrenoleukodystrophy (ALD) Mouse Model

AAPS ePoster Library, Chenxu Li, 393747

Novel Biomarkers for Inflammatory Bowel Disease

AAPS ePoster Library, Vineet Joshi, 393746

Development of a Quantitative Systems Toxicology Model to Predict Drug-Induced Liver Injury in Pediatrics

AAPS ePoster Library, An Dela, 393745

Impact of Preparation Technique and Storage Condition on the Quality of Suspension Vehicles Used in Preclinical In Vivo Studies

AAPS ePoster Library, Michael Binnefeld, 393744

Identification of Levofloxacin Hydrates and Observation of Their Crystal-Form Transition in Drug Products by Terahertz Frequency-Domain Spectroscopy

AAPS ePoster Library, Kei Shimura, 403337

Getting Sticky with It – Formulation Tenacity in 3D Printing

AAPS ePoster Library, Elke Prasad, 393742

Application of Twin-Screw Extrusion for Generating Polymorphs to Support Phase Mapping and Scale Up Crystallization of the Desired Form

AAPS ePoster Library, Henry Morrison, 393741

Analytical Case Studies for Processed-Induced and API-Related Nitrosamines in Finished Drug Products

AAPS ePoster Library, Ann Draghi, 393739

3D Printing of Single and Multi-unit Containers for Dispensing Solid Dosage Forms

AAPS ePoster Library, Hyunah Cho, 393738

Roles of Protein Corona in Physicochemical Properties and Stability of pH-Triggering Self-Assembled Nanoparticles of Drug-Myristic Acid Conjugate

AAPS ePoster Library, Dinh Hy Nguyen, 393737

Novel Melting Point Depression Method to Predict Drug Dissolution during Melt Extrusion of PLGA Millifiber Implant

AAPS ePoster Library, Coleman Johnson, 393736

Evaluating Treatment Efficiency of RV and Kinase Inhibitor (KI) in Combination for Alzheimer’s disease: Cell Line Study

AAPS ePoster Library, SAIF AHMAD KHAN, 393734

Development of a Hollow Vaginal Drug-Eluting Device Using Stereolithography 3D Printing for the Treatment of Recurrent Vulvovaginal Candidiasis

AAPS ePoster Library, Preethi Lakkala, 393733

Bioadhesive and Sustained Release Epinephrine-Loaded Sodium Alginate Hydrogel Accelerates Hemostasis to Manage Gastrointestinal Bleeding

AAPS ePoster Library, Iram Maqsood, 393732

Systematic Screening of Pharmaceutical Co-crystals Using Experimental and Computational Tools

AAPS ePoster Library, SANIKA JADHAV, 393731

Influence of Kollicream® OD on Ibuprofen Skin Permeation and Retention

AAPS ePoster Library, Gloria Ho, 393730

Analysis and Simulation of In Vivo Nanoparticle Protein Carrier Pharmacokinetics

AAPS ePoster Library, Paul Hartmeier, 393729

Exploring the Potential of Inhaled Nano Therapy for Malignant Pleural Mesothelioma

AAPS ePoster Library, Mimansa Goyal, 393728

Design and Development of High Drug Loading Commercial Formulation for a Salt Drug Substance with High Propensity of Solid Form Conversion

AAPS ePoster Library, Yi Gao, 393727

Osimertinib Immunoliposomes as Inhaled Therapy for Non-small Cell Lung Cancer Treatment

AAPS ePoster Library, Apoorva Daram, 393726

Development of an Iontophoresis-Coupled Microneedle Skin Patch of Naloxone for Emergency Treatment of Opioid Overdose

AAPS ePoster Library, Akeemat Tijani, 393725

Stabilizing High Salt Content Suspensions with Colloidal Microcrystalline Cellulose and Xanthan

AAPS ePoster Library, Yeli Zhang, 393724

Novel LAAM Immediate Release Capsule for Treating Opioid Use Disorder

AAPS ePoster Library, Zixuan Zhen, 393723

Investigating and Optimizing the Influence of Process Parameters on Development of Polymeric Microparticles: A Quality-by-Design Approach

AAPS ePoster Library, Anjali Rai, 393722

Development of Hot-Melt Extruded Solid Self-Nanoemulsifying Drug Delivery System for Improved Oral Delivery of Poorly Water-Soluble Drug Using Central Composite Design

AAPS ePoster Library, PRATEEK UTTREJA, 393721

Are Globally Marketed Generic 1% Clotrimazole Creams Pharmaceutically Equivalent?

AAPS ePoster Library, Seeprarani Rath, 393720

Novel Preparation Method of Spherical Drug-Containing Particles Using High Shear Melt Granulation; MALCORE®

AAPS ePoster Library, Naoki Yoshihara, 393719

Do the pH-Stage Dissolution Tests Lie? Case Study of Duloxetine Hydrochloride Dissolution in the Small-Scale Setup

AAPS ePoster Library, Michal Smolenski, 393718

Personalized Orodispersible Films Using Extrusion 3D-Printing: An Impending Shift in Pharmaceutical Manufacturing

AAPS ePoster Library, ISHWOR POUDEL, 393717

Development of a Discrete Element Method (DEM) Model to Study the Impact of Process Parameters and Material Attributes on Continuous Twin Screw Wet Granulation Process

AAPS ePoster Library, Tanu Mehta, 393716

Polarized Light Microscopy: A Versatile Technique in the Reverse Engineering of Entacapone Tablets

AAPS ePoster Library, Kristina Kannheiser, 393715

Tailoring Drug Release from Long-Acting Contraceptive Levonorgestrel-Containing Intrauterine Systems

AAPS ePoster Library, Suraj Fanse, 393714

Continuous Processing of Liposomal Nanoparticles as Potential Reference Materials for Drug Product Development

AAPS ePoster Library, Luke Burroughs, 393713

Pharmacokinetic and Pharmacodynamic Correlations of Riluzole and Etoricoxib in a Long-Evan Rat Model with Traumatic Brain Injury

AAPS ePoster Library, Airong Li, 393712

Rapid Quantitation of Docosahexaenoic Acid and Its Hydroxy Metabolites in Liver Cells Using Differential Mobility Separation (SelexION) Coupled with Liquid Chromatography Tandem Mass Spectrometry

AAPS ePoster Library, Vindhya Edpuganti, 393711

Duplicate-Well vs Single-Well Analysis in Ligand Binding Assays (LBAs): A Retrospective Comparison of Method Validations and Nonclinical Toxicokinetic (TK) Sample Analyses Data

AAPS ePoster Library, Md Zahir Uddin, 393709

Effect of Propofol on Lipid Membrane Fluidity and Blood-Brain Barrier Permeability

AAPS ePoster Library, Ehsan Nozohouri, 393708

Effect of Omeprazole Administration on the Pharmacokinetics of Oral Extended-Release Nifedipine: Physiologically Based Pharmacokinetic Modeling

AAPS ePoster Library, Mingliang Tan, 393707

The Impact of Surface Area per Volume Ratio on Drug Transport from Supersaturated Solutions of Ketoconazole

AAPS ePoster Library, Haruki Higashino, 393706

Characterization of Particle Disposition following Intranasal Inoculation with a 3D Printed Device

AAPS ePoster Library, Hannah Beaven, 393705

Discovery of Anti-Transforming Growth Factor β Receptor II (TGFβRII) Cyclic Peptides

AAPS ePoster Library, Mohammed Nurudeen Ibrahim, 393704

Cell Culture Media Monitoring in Cell and Gene Therapy Supporting Upstream Bioprocessing

AAPS ePoster Library, Suraj Dhungana, 393703

Novel Bio-Active Peroxisomal Proliferator Activating Receptor Gamma (PPARγ) Hydrogel for Periodontitis Management

AAPS ePoster Library, Xuejia Kang, 393701

Formulation of Cocrystal and Amorphous Solid Dispersion Printlets Developed by Hot Melt Extrusion Paired Fused Deposition Modeling for Dissolution Enhancement and Stability of Ibuprofen

AAPS ePoster Library, Tejaswini Naguboyina, 393700

Evaluating the Impact of an Ultra-High Solids Film Coating System on Process Times and Tablet Aesthetics

AAPS ePoster Library, Kapish Karan, 393699

Development of 4-phenylbutyric Acid Microsponge Formulations as a Potential Antidote for Skin Injury Due to Chemical Warfare Agents

AAPS ePoster Library, Sharvari Kshirsagar, 393698

Statistical Optimization of Stable Quercetin Nanoparticles for Tumor Targeting

AAPS ePoster Library, Purnajai Srivijay Saravanan Vanaja, 393697

Evaluation of the Compatibility of Capsugel® Enprotect® Capsules with Solid Phase Excipients to Accelerate Developments of New Enteric Drug Products

AAPS ePoster Library, Vincent Jannin, 393696

Increasing Oxidative Stability with High Purity Excipients Used in Ophthalmic Formulations

AAPS ePoster Library, Kritika Bajaj, 393694

Demonstrating the Utility of a New High Molecular Weight HPC to Make Smaller Modified Release Tablets

AAPS ePoster Library, Teslin Botoy, 393695

Role of Polymers in the Physical and Chemical Stability of Amorphous Solid Dispersion: A Case Study of Carbamazepine

AAPS ePoster Library, Dongyue Yu, 403313

Formulation and In Vitro Characterization of Orally Disintegrating Tablets of Drug Molecules with Varied Physicochemical Properties

AAPS ePoster Library, Pramila Sharma, 403312

Surfactant Selection in the Development of Oral Ternary Amorphous Solid Dispersions from the Perspective of Solubility and Supersaturation

AAPS ePoster Library, Dijia Liu, 403310

Viable Eukaryotic Cell Dry Powders Prepared by Thin Film Freeze-Drying

AAPS ePoster Library, Mahmoud Hanafy, 403286

pRNA Nanoparticles for Ocular Delivery: Pharmacokinetics and Pharmacodynamics After Subconjunctival Injection

AAPS ePoster Library, Cheng Zhong, 403287

Development of Hydroxypropyl Methylcellulose (HPMC)-Based, Titanium Dioxide (TiO2)-Free Coating

AAPS ePoster Library, Dominika Czernik-Schulz, 403288

Equilibrium Solubility, Thermodynamic Modeling and Solubility Parameters of Itraconazole in Solvent Mixtures at Various Temperatures

AAPS ePoster Library, Hui-Taek Kang, 403289

Using Biorelevant Dissolution to Better Predict Bioavailability Issues

AAPS ePoster Library, Sonia Lombardo, 403290

Orally Disintegrating Tablet Formulation of Vardenafil Taste-Masked Pellets

AAPS ePoster Library, Santhosh Punnoose, 403291

Quantitating the Contributions of the Particle Drift Effect to In Vitro FLUX and the Application of Particle Drift Flux to Predictive Modelling

AAPS ePoster Library, Balint Sinko, 403292

In-Cell ELISA Assays to Assess Drug Relative Potency Using the Cytation Imaging Reader for Sample Analysis

AAPS ePoster Library, Leigh Laundon, 403293

Simultaneous Determination of Naphazoline Hydrochloride and Pheniramine Maleate Along with Their Related Compounds by High Performance Liquid Chromatography

AAPS ePoster Library, Fadi Alkhateeb, 403294

Principle Component Analysis of Formulation Variations on Binder Jet 3D Printed Tablet

AAPS ePoster Library, Daniel DeNeve, 403295

An Improved Multiple Headspace Extraction Workflow Using SIFT-MS

AAPS ePoster Library, Paul Johnson, 403296

Performance of Pre-Filled Syringe Systems at Low Temperature

AAPS ePoster Library, Page McAndrew, 403297

3D Printed Medication: A Case Study on Personalization of Pediatric Arrhythmia Treatment

AAPS ePoster Library, Jayeeta Sengupta, 403298

Mechanistic Determination of Tensile Strength of Shaped Tablets

AAPS ePoster Library, Bereket Yohannes, 403299

Advancing Neuro-Regenerative Therapies: Scalable Manufacturing and Purification of Extracellular Vesicles for Treating Neurodegenerative Diseases

AAPS ePoster Library, Nasser Nassiri Koopaei, 403301

Tocilizumab Induced Immunosuppression in A Case of Adult-Onset Still’s Disease: Are These Newer Biologics Double Edged Sword?

AAPS ePoster Library, Hirva Sureshbhai Santoki, 403302

Assay Development and Characterization of T. gondii Nucleoside Transporters in MDCK-II Cells

AAPS ePoster Library, Yewei Du, 403304

Effects of Clarithromycin on the Pharmacokinetics of Pitavastatin and Its Lactone Metabolite in Different SLCO1B1 Diplotypes

AAPS ePoster Library, Pureum Kang, 403305

Evaluation of Applications for Topical Semisolid Drug Products with In Vitro Permeation Test and In Vivo Bioequivalence Study with Pharmacokinetic Endpoints

AAPS ePoster Library, Hao Liu, 403306

Delivery of Therapeutic Plant-Derived Exosomes to the Brain for the Treatment of Mental Health Disorders and CNS Injuries

AAPS ePoster Library, Nasser Nassiri Koopaei, 403307

Thermally Gelling Hypromellose Liquid Sprays for Oropharyngeal Targeting

AAPS ePoster Library, Ansley Battle, 403308

Sweet Levofloxacin Acesulfame Crystals with Improved Compaction Property and Solvates Interconversion

AAPS ePoster Library, Pin-Syuan Huang, 403309

Analytical Characterization for Nucleic Acid Therapy: A Case Study

AAPS ePoster Library, Rute Mota, 403280

Calcium Carbonate as an Alternative to Titanium Dioxide in Coating: The Importance of Particle Engineering

AAPS ePoster Library, Giovanni Raspantini, 403279

Metabolite Identification of Nucleoside Analog Prodrugs in Biological Matrix by Derivatization Coupled with Radio-Detector and Mass Spectrometry

AAPS ePoster Library, Lingling Zhang, 403278

Enhanced Mechanistic Understanding of Drug Product Performance Via High-Resolution Imaging and AI Image Analytics

AAPS ePoster Library, Phillip Yawman, 403277

Optimization of the Continuous Direct Compression Process with Special Focus on Filling Devices

AAPS ePoster Library, Simon Schulte Herbrüggen, 403276

Development and In Vitro Evaluation of Donepezil, Memantine and siRNA Encapsulated Liposomes

AAPS ePoster Library, David Lee, 393658

Application of Ac-Di-Sol® SD-711 in Orally Disintegrating Tables (ODTs): Performance Comparison of Croscarmellose Sodium and Crospovidone

AAPS ePoster Library, Zahra Mahmoudi, 393657

Evaluation of Critical Quality Attributes (CQA’s) of Carbomer Based Topical Hydro Gels with Process Analytical Technique (PAT)

AAPS ePoster Library, Bhavana Chivukula, 393654

Novel Expandable Platform for Retentive Drug Delivery Systems

AAPS ePoster Library, Matteo Cerea, 393653

Immunity for the Long Haul: Exploring Cross-Protectivity against Emerging Strains upon Vaccination with Gonococcal Vaccine Microparticles in Mice

AAPS ePoster Library, Priyal Bagwe, 393652