High-Resolution Sequencing Comparison of the DNA Methylome and Hydroxymethylome in Leukemia and Normal Blood Cells
AAPS ePoster Library, Tamer Fandy, 393308
Development of Oral Bi-layer Tablet of Ruxolitinib
AAPS ePoster Library, Namhyuck Kim, 402998
Effect of Different Neutralizers and Their Concentration on Enteric Coating of Hypromellose Phthalate (HPMCP HP-50) and Drug Release in Various pH
AAPS ePoster Library, Arun D'Souza, 402997
Low Dose Compatibility Testing With and Without Surfactant in Polyethylene Terephthalate (PETG), Glass, and Polypropylene Container Types for Large Molecule Analysis
AAPS ePoster Library, Andrew Kuhn, 402996
Mechanistic Modeling of In Vitro Biopharmaceutic Experiments for a Weakly Dibasic Drug for Incorporation into PBPK Models
AAPS ePoster Library, Venkata Krishna Kowthavarapu, 402995
Focus on Efficacy: In Vitro Tissue Models for Preclinical Research
AAPS ePoster Library, Christina Fey, 402994
Past-to-Present Comparison of Repeat Analysis-Related Observations in Pharmacokinetic Bioequivalence Studies Submitted in Abbreviated New Drug Applications
AAPS ePoster Library, Alaa AbuZnait, 402993
Masking Strategies for Immune Checkpoint Inhibitors to Decouple Adverse Events in Cancer Treatment
AAPS ePoster Library, Seokho Song, 402992
Prospectively Assessing the Immunogenic Risk of Potential Synthetic Peptide Impurities In Silico Using the What-if Machine (WhIM)
AAPS ePoster Library, Riley Nolan, 402991
Quantification of Oligonucleotide Therapeutics in Plasma Using a Generic Kit-Based Approach
AAPS ePoster Library, Margot Lee, 402990
Physiologically Based Pharmacokinetic (PBPK) Modeling of Fexofenadine and Assessment of Transporter DDIs of Fexofenadine with P-gp Inducers and Inhibitors
AAPS ePoster Library, Suvarchala Avvari, 402989
A Tactic for Resolving Lactose Matrix Interference with Residual Heptane in GC Analysis of an API cPAD Formulation
AAPS ePoster Library, Van Truong, 402988
Scale-Down Modeling of the Filling Process for Protein-Based Parenteral Drug Products
AAPS ePoster Library, Camilla Moino, 402987
Terahertz Pulsed Imaging (TPI) Based Liquid Transport Profiling For the Tablet Disintegration Process Analysis
AAPS ePoster Library, Jongmin Lee, 402986
CryoTEM Imaging of Onivyde for Precise Reverse Manufacturing
AAPS ePoster Library, Jingyao Gan, 402985
Screening Chiral Stationary Phases in Multiple Separation Modes to Identify a Method for the Enantiomeric Separation of Modafinil
AAPS ePoster Library, Jonathan Sanchez, 402984
Identification of Isomerization in IgG1 and Its Impact on Potency: Case Study of a Mab Biosimilar
AAPS ePoster Library, Shalini Sharma, 402983
Reliable Sizing of Lipid Nanoparticles in Concentrated Formulations Using Advanced Dynamic Light Scattering
AAPS ePoster Library, Ian Block, 402982
Comparison of Branched DNA (B-DNA) and Polymerase Chain Reaction (RT-qPCR) Method Validation for the Quantification of mRNA Therapeutics in Plasma
AAPS ePoster Library, Maotian Zhou, 402981
Increased Throughput for Regulated Bioanalysis with Catch-and-Hold Mode of HPLC Separation with High Sensitivity Mass Spectrometers
AAPS ePoster Library, Bibo Xu, 402980
Enhanced Pharmacokinetic Bioanalysis of Antibody-Drug Conjugates Using Hybrid Immunoaffinity Capture and Microflow LC-MS/MS
AAPS ePoster Library, Jiaqi Yuan, 402979
Quantitation of Bemnifosbuvir and Metabolites in Human Bronchoalveolar Lavage (BAL) by LC-MS/MS
AAPS ePoster Library, Jeff Plomley, 402978
Elements of Robust Modified Oligonucleotide Extraction through SPE
AAPS ePoster Library, Makda Araya, 402976
Development of a Water-Soluble Mini-Tablet Formulation for Flow Cytometry Applications
AAPS ePoster Library, Nathan Spurgin, 402975
Theoretical and Experimental Polymer-Polymer Miscibility Prediction: An Insight to In Vivo Compatibility
AAPS ePoster Library, Saad Niaz, 402974
Assessment of Stability and Erosion Behavior of ASDs by Using VCM Technique
AAPS ePoster Library, Vanessa Havenith, 402973
Dynamic In Vitro Cell Culture Model to Study Pathogenic Interactions in Periodontitis In Flow Using a Lab-on-a-Disc Platform
AAPS ePoster Library, Juliane Christfort, 402972
Bioequivalence Prediction Based on In Vitro Flux Assay through the Example of Aripiprazole
AAPS ePoster Library, Balint Sinko, 402971
Optimization of Roller Compaction Process Parameters for a Poorly Soluble Drug Using Quality by Design Tool
AAPS ePoster Library, Kuntal Parikh, 402970
The Effect of Controlled After-Melt Cooling Rate on Amorphization Degree of High-Drug Loaded Solid Dispersions of a Poor Glass-Forming Drug
AAPS ePoster Library, Dijia Liu, 402969
Film-Coated Hard Capsules for Dry Powder Inhalers: Improving Inhalation Efficiency and In-Use Stability
AAPS ePoster Library, Jin-Hyuk Jeong, 402968
New Insight into the Oral Delivery Mechanism of Semaglutide Based on All-atom Molecular Dynamics Simulations
AAPS ePoster Library, Severin Schneebeli, 402966
Boosting Antitumor Immune Response against Breast Cancer Cells Using Doxorubicin and Zinc Oxide Nanoparticles Co-loaded Lipid Nanocarrier
AAPS ePoster Library, Hend Mohamed Abdel-Bar, 402965
Benchmarking Large Multi-task Machine Learning Models for ADME, Toxicology and Drug Discovery Endpoints
AAPS ePoster Library, Sean Ekins, 393386
The Impact of Relative Humidity on In Vitro Permeation Test Method Performance Indicators, Jmax, Tmax and Amount Permeated for Molecule, TER-003
AAPS ePoster Library, Deepal Vora, 393323
Predicting the Stability of Amorphous Formulations Mixtures with Terahertz Spectroscopy
AAPS ePoster Library, Supawan Santitewagun, 393322
Mannose Functionalized Chitosan Coated PLGA Nanoparticles for Cannabidiol Delivery to the Brain for the Treatment of Alzheimer’s disease
AAPS ePoster Library, Jagdish Singh, 393321
Formulation Optimization of EVX-101, a Novel Gastro-Retentive Prolonged-Release 5-HTP/Low-Dose Carbidopa Tablet
AAPS ePoster Library, Aurna Railkar, 393320
Drug-Free Bioresponsive Hydrogel for On-Demand Contraception
AAPS ePoster Library, Burcu Uner, 393319
Characterization of Compression Behavior of Co-processed Excipient for Production of Orally Dispersible Tablets and of Their Blends with Active Ingredient
AAPS ePoster Library, Piero Piccinni, 393318
A Comparative Study of In Vitro Itraconazole Drug Release from Amorphous Solid Dispersions (ASDs): Sempera® and Tolsura® under Fed State Conditions
AAPS ePoster Library, Niklas Rudolph, 393317
Worsened Punch Sticking by External Lubrication with Magnesium Stearate
AAPS ePoster Library, Tianyi Xiang, 393316
Use of Granulation and E-Tongue for Taste-Masking of an Orally Disintegrating Tablet (ODT)
AAPS ePoster Library, Adriana Quiroga, 393315
Advancements in Mini-Tablets: High Drug Loading and Precise Dose Titration
AAPS ePoster Library, Frantisek Stepanek, 393314
Modern Liquid Chromatographic Gradient Method Allowances Provided by General Chapter, USP Chromatography < 621 >
AAPS ePoster Library, Catharine Layton, 393313
Beneficial Effects of Trehalose on Mesenchymal Stem Cell-Derived Exosomes
AAPS ePoster Library, Kotaro Hashimoto, 393304
Design and Synthesis of Conformationally Modulated Rutinose Saccharides and Their Conformational Analysis by NMR
AAPS ePoster Library, Dhwani Mehta, 393305
A Compatibility Test of Two-Piece Hard Capsules and Liquid/Semi-solid Excipients - Part 2
AAPS ePoster Library, Mamoru Honda, 393306
Sodium Butyrate Decreases VCAM-1 Expression by Inhibiting Stat3/GATA6 Signaling Pathway in Alzheimer’s disease
AAPS ePoster Library, Vrishali Salian, 393307
Interaction of Thermal and Rheological Parameters Critical for the Processability of Polyvinyl Alcohol-Based Systems during Hot Melt Extrusion
AAPS ePoster Library, Giovanni Raspantini, 403000
Associations of Polymorphisms of the ABCB1 and ABCC2 Genes with Cisplatin-Induced Nephrotoxicity and Myelosuppression in Patients with Head and Neck Cancer
AAPS ePoster Library, Eder Pincinato, 393309
Novel Strategies for Process-Related Impurity Clearance during Biologics Manufacturing
AAPS ePoster Library, Aba Acquaah, 393310
Design, Development, and Evaluation of Novel Extended-Release Liposomal Topical Cream Formulation of Pregabalin Using Microemulsion Technique for the Treatment of Local Neuropathic Pain
AAPS ePoster Library, Chetan Chure, 393311
Peak Shear and the Effect of Kneading Block Geometries on Twin Screw Granulation Process Design
AAPS ePoster Library, Brian Haight, 393312
An Orthogonal Bioanalytical Approach to Assess the Immunogenicity and Efficacy of Covid-19 Vaccines
AAPS ePoster Library, Thangamma Subramani, 376806
Sensitization of Paclitaxel-Induced Apoptosis by Echinops giganteus Extract via Downregulation of PI3K/Akt/NF-κB Pathway and Enrichment of TIMP-3 in Cervical Cancer
AAPS ePoster Library, Ahmed Somaida, 376805
Importance of Quality Control of In Vitro Transcribed RNA
AAPS ePoster Library, Patrick Schindele, 376804
Multiple Root Causes Impact Methionine Oxidation in a Coformulated Drug Product
AAPS ePoster Library, Jorge Pavon, 376803
Mechanistic Investigation of Side-Effects of Lung Tropic Lipid Nanoparticles
AAPS ePoster Library, Serena Omo-Lamai, 376802
A Sensitive Electrochemiluminescence-Based Method for the Detection of Anti-drug Antibodies against Anti-PD-1 Antibody Drug Pembrolizumab in Human Serum
AAPS ePoster Library, Nikki Keasey, 376801
Bioanalytical Cross Validation: A More Statistically Based Approach to Establish Differences between Bioanalytical Methods and Laboratories
AAPS ePoster Library, Mianzhi Gu, 376800
Preparation of PEG-b-PLA Nanoparticles via Inline Sonication for Controlled Release Applications
AAPS ePoster Library, Fei Liu, 376799
Alginate Hydrogels: A Tunable Tool for Biotech Applications
AAPS ePoster Library, Joshua Katz, 376798
Multiplexed Quantification of CAR-T Subtypes by PCR
AAPS ePoster Library, Kevin Lee, 376797
Preparation and Evaluation of Protein Encapsulated Liposome Using Surfactant for Dry Powder Inhalation
AAPS ePoster Library, Junwoo Park, 376796
Validation of PBPK-Based Translation to Predict Monoclonal Antibody Pharmacokinetics in Pediatric Populations
AAPS ePoster Library, Jessica Spires, 376795
Characterization and In Vivo Evaluation of Oil Based Anti-adhesion Agent with Xanthan Gum
AAPS ePoster Library, Jaekwan Jeong, 376793
Harnessing Dendritic Cell Migration as a Predictor of Subcutaneous Immunogenicity Risk in a Mechanism-Based Screening Tool
AAPS ePoster Library, Nicole Jarvi, 376792
Screening and Epitope Binning of Anti-idiotypic Antibodies against Therapeutic Bispecific Antibodies Using the Gyros Immunoassay Platform
AAPS ePoster Library, Yury Chaly, 376791
ST266 Amnion-Derived Mutipotent Cell Secretome for Prevention and Treatment of Necrotizing Enterocolitis
AAPS ePoster Library, Larry Brown, 376790
Effect of Different Types of Dendrobium on the Gut Microbiota Alteration and Anti-diabetic Effect: In Vitro Screening and In Vivo Verification in db/db Mice
AAPS ePoster Library, Zhong Zuo, 376789
Labelling AAV5 Capsid Reduced Its Binding Affinity to the Anti-AAV5 Antibody in Non-primate Human Serum Samples
AAPS ePoster Library, Mengmeng Zhai, 376788
Current Strategies for Using Commercial Kit in Regulated Bioanalysis
AAPS ePoster Library, Vaibhav Mehta, 376787
Development and Optimization of Next-Generation Lipid Nanoparticles for In Situ CAR-T Production
AAPS ePoster Library, Bumjun Kim, 376786
CARTs - A New Vehicle for Nucleic Acid Delivery with a Unique Controllable Release Mechanism
AAPS ePoster Library, Zahra Merchant, 376785
Validation of an Anti-drug Antibody (ADA) Assay Using the Mitra VAMS Microsampling Technology in Support of a Phase I Clinical Study
AAPS ePoster Library, Marina Ichetovkin, 376784
Development of RT-qPCR Assay to Quantify mRNA in the Biodistribution Study of mRNA-Based Vaccines
AAPS ePoster Library, Zhongying Chen, 376783
Evaluating a Merged Well Analysis Strategy for Validation of a Cellular Kinetics Assay to Quantify an Allogeneic Cell Product in Human Blood by ddPCR
AAPS ePoster Library, Brian Bower, 376782
Strategies for Measuring Oligonucleotides Using a Fully Automated Microfluidic Immunoassay System
AAPS ePoster Library, John Chappell, 376781
Conjugation Chemistry Used to Construct Protein-Coated Nanoparticles Determines Complement Activation and Associated Efficacy and Toxicity
AAPS ePoster Library, Michael Zaleski, 376780
Evaluation of Formation of SpyTag Form of Botulinum Toxin A (BoNT/A) by Electrochemiluminescence Sandwich Immunoassay
AAPS ePoster Library, Erik Wagner, 376779
Detection and Quantification of AAV Genome: Effects of Sample Pretreatment and Cross Platform Comparison of ddPCR and qPCR
AAPS ePoster Library, Carrie Vyhlidal, 376778
Assessing the Feasibility and Impact of Singlicate-Based Analysis for Clinical ADA Sample Analysis
AAPS ePoster Library, Patricia Stephens, 376777
Short-Term Tacrolimus/Sirolimus Combination Therapy Induces Long-Term Immune Tolerance to a Human Monoclonal Antibody in Rats
AAPS ePoster Library, PARIDHI GUPTA, 376776
Tolerization with a Novel Tim Agonist Dual-Acting Liposomal Formulation Prepares the Immune System for the Success of Gene Therapy
AAPS ePoster Library, Abdulraouf Ramadan, 376775
Modification of Particle and Hardware Surfaces for Efficient Biotherapeutic Method Development
AAPS ePoster Library, Pawel Bigos, 376774
Selectivity of Human Cytokine Quantification in Human and Cyno Serum Using a Fully Automated Microfluidic Immunoassay System
AAPS ePoster Library, James Sharkey, 376773
Antibody Titration: Titer Cut-Point or Screening Cut-Point: Which One Is a Practical Option?
AAPS ePoster Library, Thangamma Subramani, 376772
Bridging of a Duplex to Singleplex bDNA Method to Quantitate mRNA from LNP-mRNA-ABC in Human Serum
AAPS ePoster Library, Jennifer Patel, 376770
Immunocapture LC-MS/MS Assay for the Biomarker, Troponin Fast (TNNI2) Using a Specific Antibody
AAPS ePoster Library, Shane Needham, 376769
Brain-Targeted Delivery of Plasmid DNA Encoding for Angiotensin II Receptor shRNA to Manage Neurogenic Hypertension
AAPS ePoster Library, Richard Lamptey, 376768
Achieving Drug Tolerance in a Multiplexed Neutralizing Antibody Assay (nAb) Using Competition and Heat Solid Phase Extraction (SPE) Conditions
AAPS ePoster Library, Andrew Goodyear, 376767
Approaches for Reducing the Environmental Impact and Increasing the Throughput of Bioanalytical LC Separations
AAPS ePoster Library, Edward Faden, 376766
Discrepancies in Adeno-Associated Virus Serotype and Isotype Characterization Positivity Rates in Cynomolgus Serum
AAPS ePoster Library, Molly Crowe, 376765
Application of Mitra Microsampling for the Quantitative Bioanalysis of Antisense Oligonucleotides
AAPS ePoster Library, Kevork Mekhssian, 376761
High-Throughput and Selective LC-MS Quantitation of SMARCA2/4 for SMARCA2 Targeted Protein Degrader Cross-Species Pharmacodynamics Analysis
AAPS ePoster Library, Zihui Li, 376760
FM1000 Surfactant is Compatible with Downstream Bioprocessing
AAPS ePoster Library, Joshua Katz, 376759
A Robust Adoptive Cell Therapy Phenotyping Panel for Assessing Cerebrospinal Fluid During and After Neurotoxicity by Flow Cytometry
AAPS ePoster Library, Jane Craig, 376758
Developing a Generic ADA Assay for the Detection of Circulating Immune Complexes Using a Fully Automated Microfluidic Immunoassay System
AAPS ePoster Library, James Sharkey, 376757

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